- Este event já passou.
Minicurso na Área de Processos Fotodinâmicos na UFABC.
08 ago 2016 - 12 ago 2016
Course Title: “Photodynamic processes: shining light on sensing and actuating in biological systems”
Lecturer: Dr Francesca Giuntini is a Lecturer of Medicinal Chemistry at the School of Pharmacy and Biomolecular Sciences in Liverpool John Moores University (Liverpool, UK). Her research interests focus on the development of porphyrin-based photosensitisers to promote photodynamic oxidations in biological environment.
Overview: Reactive oxygen species (ROS) are unstable derivatives of oxygen (e.g., peroxides, superoxide, hydroxyl radicals, and singlet oxygen) that play crucial roles in numerous chemical and biological processes. At low concentration, ROS are important signalling mediators of a number of cellular functions, while high intracellular levels results in oxidative stress, and a number of degenerative phenomena (e.g. cancer). If harnessed, however, the high reactivity of ROS is a powerful tool to interrogate and influence the behaviour of biological systems. Indeed, in the past decades the light-triggered (i.e., photodynamic) production of ROS has been exploited for therapeutic purposes (e.g.,in photodynamic therapy) and for environmental application (e.g., photoremediation of wastewater). In this course we will explore the molecular bases of photodynamic processes and the current applications in the biomedical field.
- Molecular bases of photodynamic processes
- The chemistry of photodynamic: photosensitiser at molecular- and nanoscale
- Photodynamic oxidations in biological systems
- Therapeutic applications of photodynamic processes
- Photodynamic remediation of wastewaters
- Photodynamic processes as tools for biochemical investigation
The course will comprise lectures and workshops, and will be delivered from the 8th to 12th of August for a total of 20 hours (4 hours per day). The course will be delivered in English.
Applications: From 25.07.2016 to 02.08.2016
To more information visit: http://ppgquimica.ufabc.edu.br/